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Science is One Step Closer to Cloning a Race of Super Humans
Sep 16th, 2016
Daily NewsPHILIP PERRY
Categories: Contemporary Issues

Most of us like the idea of superpowers. Though we may never have the strength of Superman, we could be made stronger, faster, and even better-looking, with total control over our genome, or genetic makeup. What about becoming disease-resistant, weight gain resistant, and even slowing down the aging process? This might be possible in decades to come, as geneticists are now getting ever closer to, not just removing and replacing genes, but rewriting entire genomes. It sounds like the realm of science fiction. Yet, consider that geneticists at Harvard recently recoded the genome of a synthetic E. coli bacteria. Prof. George Church and colleagues conducted the study.

Researchers replaced 62,214 base pairs of DNA. What they have done is recreate the DNA from scratch, though they haven’t actually brought the bacteria to life, yet. What was once thought impossible is no longer. This is the first synthetic genome ever assembled, and is being hailed as the most complex feat of genetic engineering, thus far.

With this technique, we could create any kind of life form we wanted, reprogram organisms, and even create synthetic proteins and compounds. MIT bioengineer Peter Carr, told the journal Science, "It's not easy, but we can engineer life at profound scales.” Note that he was not involved in this project. So how exactly are they rewriting a genome? DNA is made up of four nucleobases which arrange themselves as base pairs, A and T, C and G. These create one strand of the double helix, known as RNA.

Each combination equates to a certain amino acid, which is what cells are essentially made up of. Cell’s read combinations of nucleobases to know which amino acids to produce. There are only 64 possible combinations. When put in a group of three—called codons, they create a certain kind of amino acid. There are 20 different kinds in total. C-C-G for instance creates the amino acid proline. C-C-C does as well. So there is some overlap. In this way, geneticists can erase redundant genes without affecting the development of the organism.

That’s what Harvard geneticists did here. They edited out the overlap. Scientists removed seven of 64 codon types throughout 3,548 genes. Instead of editing the genome one gene at a time, researchers used machines to synthesize whole segments of RNA from scratch, each portion containing several alterations. Then they inserted these segments into the E. coli’s DNA, one-by-one, making sure as to not make changes that would destroy the cell. So far, 63% of recoded genes have been tested. Very few have caused any problems for the cell. Researchers still have several years of experimentation and testing ahead. Still, geneticists are marveling at how malleable the genome actually is.

In the near term, scientists are excited about the prospect of creating bacteria that is invulnerable to viruses. Usually, a virus infects a living cell by adding its own DNA to the host’s genome. In this way, it replicates itself. Genetically recoded organisms (GROs) would have a genome so different, the virus wouldn’t be able to read it and so couldn’t inject its DNA, making it unable to replicate.

One possible use for GROs is manufacturing. By rewriting a bacterium’s genetic code, it would change what kind of protein it makes. Synthetic bacteria could become living factories, programmed to produce whatever amino acid wished for. These would then churn out the next generation of synthetic materials, perhaps even medicines. Such engineered bacteria could also become reliable test subjects for future scientific research.

Prof. Church’s experiments have been controversial in the past. In that, one issue is whether or not this technique is 100% safe. The concern is that recoded bacteria could produce a toxin. Since it would be resistant to viruses, it would have an edge over competitors in the environment. If it should say get loose, it could result in ecological damage or even cause the next great plague. To overcome this concern, Church and colleagues have built a few safety measures into the system.

A special nutrient must be fed to these bacteria or else they die off. Unless they find this selfsame nutrient in the environment, which Church says is unlikely, they would not be able to survive. Another fail-safe is a special barrier which has been erected to make it impossible for the bacteria to mate or reproduce, outside of the lab. But other experts wonder how “unbeatable” Church’s fail-safe’s actually are. Carr says that instead of discussing these measures as foolproof, we should be framing it in degrees of risk.

The next step is further testing of the artificial genes that have been made. Afterward, Church and colleagues will take this same genome and produce an entirely new organism with it. Since DNA is the essential blueprint for almost all life on earth, being able to rewrite it could give humans an almost god-like power over it. That capability is perhaps decades away. Even so, combined with gene editing and gene modification, and the idea of a race of super humans is not outside the realm of possibility.

Let the Headlines Speak
Sep 16th, 2016
Daily NewsFrom the Internet
Categories: Today's Headlines

2 more docs charge coverup in Hillary health scandal
Dr. Jane Orient, executive director of the Association of American Physicians and Surgeons, told WND the letter from Bardack “ignores all the pertinent questions.” “Maybe she has pneumonia, but the timing is perfect for explaining a fall we weren’t supposed to see and which could have been caused by same neurological damage that caused previous falls,” she said.  

Two-state solution to Israel-Palestine conflict at risk of giving way to ‘one-state reality,’ warns Ban
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Will Putin push Israel to talks with the PA?
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Magnitude 5.5 Earthquake Strikes Off Indonesia’s Coast, No Tsunami Threat Read more: https://sputniknews.com/asia/20160916/1045359203/magnitude-5-qua
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Obama gathers advisers amid unease over Syria deal
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UN's Ban: Netanyahu ethnic cleansing remarks 'outrageous'
UN Secretary General Ban Ki-Moon has criticised Israel's prime minister for saying Palestinians want the "ethnic cleansing" of Jews in the West Bank. Benjamin Netanyahu's use of the term in a video attacking opponents of Jewish settlement construction on occupied territory was "outrageous", he said.  

France labour reform: Clashes during 'last round' of street protests
Riot police clash with protesters in France marching against labour reforms in what unions say will be the last of such demonstrations. Protesters gathered in Paris and other French cities to demonstrate against a controversial French labour reform that aims to make it easier to hire and fire workers and negotiate directly with employees on working time.  

At the epicentre of Delhi's chikungunya epidemic
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MKs call for greater religious pluralism following ‘Post’ poll
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In a hungry Venezuela, buying too much food can get you arrested
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Philippines is not 'little brown brother' of U.S.: foreign minister
The Philippines is firmly committed to its alliance with the United States but will not be lectured on human rights and treated like a "little brown brother," the country's Foreign Minister Perfecto Yasay said on Thursday.  

The Era of American Global Dominance Is Over
You might recall the term “Eurasia” from high school geography classes. The term isn’t used much anymore in political discussions in the West, but it should be. That is where the most serious geopolitical action is going to be taking place in the world as we move deeper into the 21st century. The U.S., focused so intently on “containment“ of Russia, the so-called Islamic State and China, will be missing the bigger Eurasian strategic picture.  

Embassy stay risks Assange's mental health: WikiLeaks
WikiLeaks on Thursday released medical records claiming its founder Julian Assange's mental health was at risk if he remained in the Ecuadorian embassy in London, ahead of a court hearing in Sweden to decide whether to maintain an arrest warrant for him.  

ISIS' deadliest ally has started fighting itself
“You can’t really be more barbaric and more savage ...," Issoufou Yahaya, a political analyst at Niamey University in Niger, told The Wall Street Journal.  

Science is One Step Closer to Cloning a Race of Super Humans
What they have done is recreate the DNA from scratch, though they haven’t actually brought the bacteria to life, yet. What was once thought impossible is no longer. This is the first synthetic genome ever assembled, and is being hailed as the most complex feat of genetic engineering, thus far. With this technique, we could create any kind of life form we wanted,  

Four Studies Find ‘No Observable Sea-Level Effect’ From Man-Made Global Warming
Ten years after former Vice President Al Gore warned in his 2006 Oscar-winning film, An Inconvenient Truth, that if nothing was done to stop man-made global warming, melting Antarctic and Greenland ice sheets could raise sea levels by up to 20 feet, four peer-reviewed scientific studies found “no observable sea-level effect of anthropogenic global warming.”  

New Horizons' data continues to uncover surprises on Pluto and its moon
As a cold, rocky planet that doesn't have a magnetic field, Pluto itself shouldn't be able to emit X-rays – and yet, the Chandra X-ray Observatory has found that it does.  

Obama, Clinton Guilty of ‘Christophobia’ Amid Refugee Crisis
Johnnie Moore, a Christian author and humanitarian, is slamming President Barack Obama and Democratic presidential nominee Hillary Clinton for their action — or inaction — when it comes to the Christians currently facing “genocide” in the Middle East. “If you’re anti-Christian, henceforth, you are guilty of Christophobia,” Moore said. “You are a Christophobe. You are exhibiting Christophobic behavior, and we’re going to shame you with it.”  

Kentucky Gov. Matt Bevin says bloodshed may be needed to protect conservatism
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2 More Docs Charge Coverup in Hillary Health Scandal
Sep 16th, 2016
CommentaryWND
Categories: Contemporary Issues

With a significant number of top physicians expressing concern that the American people aren’t being told the truth about Hillary Clinton’s health, the Democratic Party nominee’s personal doctor is declaring she is fit to return to the campaign trail.
The letter from Dr. Lisa Bardack was distributed by the campaign Wednesday after a video of Clinton apparently collapsing as aides helped her enter her limousine during a 9/11 memorial Sunday confirmed suspicions over the past several months that she is seriously ill.

Concerns about reported fainting spells, stumbles, blood clots, uncontrollable coughing and a “serious” concussion that took “months,” however, are being attributed to “dehydration,” “flu” or “pneumonia” by her campaign.

Bardack works in the internal medicine section at CareMount Medical in Mount Kisco, New York.

“My overall impression,” she wrote,” is that Mrs. Clinton has remained healthy and has not developed new medical conditions this year other than a sinus and ear infection and her recently diagnosed pneumonia. She is recovering well with antibiotics and rest. She continues to remain healthy and fit to serve as president of the United States.”

But her two-page letter addressed none of the issues captured on video, including her violent head-jerking in one episode and her blank stare and loss of focus in another.

Dr. Jane Orient, executive director of the Association of American Physicians and Surgeons, told WND the letter from Bardack “ignores all the pertinent questions.”

“Maybe she has pneumonia, but the timing is perfect for explaining a fall we weren’t supposed to see and which could have been caused by same neurological damage that caused previous falls,” she said.

Dr. Lee Hieb, author of “Surviving the Medical Meltdown: Your Guide to Living Through the Disaster of Obamacare,” took no time in expressing alarm.

“From a distance, without formal evaluation there are still three things I know for sure regarding Hillary Clinton’s medical condition: 1) She has a neurological disorder; 2) pneumonia did not cause the episode on 9/11; and 3) she and her staff have been lying to cover up the truth of her condition for months if not years.”

She explained: “I practice orthopedics and am fellowship trained in spinal surgery. As such, I do quite a lot of neurological valuation in my clinic. And as an orthopedic surgeon, I take care of fractures in elderly people who fall. Now, everyone falls occasionally, and as we get older we fall a little more frequently. But even people with loss of sensation in their feet, people with weak muscles and people with chronic conditions like cancer don’t fall that frequently. There are only two groups of people who fall a lot – raging alcoholics and people with neurological disorders. If Hillary were drinking herself into falling, she would not have been able to perform at her usual job/campaign. But, for over a year, she has fallen on camera and behind camera. We are told of heat stroke, dehydration and other reasons to justify multiple falling episodes. She has fallen and broken her elbow and fallen and hit her head hard enough apparently to cause bleeding.

“And let’s look at how she is falling. After the 9/11 ceremony, she is seen ‘collapsing’ on the way to her vehicle. Now people who faint due to low blood pressure, sudden illness, heat stress, etc. slump limply. They are easy to support and care for. Not so Hillary’s episode. Watch it yourself and you will see she is rigid and in spinal extension. After a few seconds of wrestling that abnormal posture her handlers are able to get her into the car.”

Hieb said pneumonia “does not explain any of this.”

“Her staff may have decided – because coughing is often associated with pneumonia – that they could get away with blaming her problems on that condition. But not so fast. Any doctor who has treated pneumonia can affirm that if you are sick enough to pass out, you are not going to recover in an hour to become a smiling, waving Hillary exiting her daughter’s condo. And her cough is chronic. Are we really expected to believe her doctors couldn’t make a diagnosis of pneumonia – if that’s what it is – after months to years of cough? Like take an X-ray? Recently chronic cough has been shown to often be neurogenic in nature. It is associated with stroke and can be ameliorated with spinal cord modulating drugs such as gabapentin. So there is a more probable explanation to her cough.”

She then brought all the evidence together.

“I knew she must have a neurological disorder but had dismissed Parkinson’s because of her facial animation. Parkinson’s is characterized by ‘frozen’ face – patients are without normal smiling, etc. But it was pointed out by other more astute clinicians that head bobbing and exaggerated eye and facial movement is seen in late treatment of Parkinson’s patients on chronic levodopa – the classic medical intervention,” she said.

“Parkinson’s is a disease of group of diseases where patients have neurological symptoms due to loss of the neurotransmitter dopamine. It is characterized by rigidity, flat facial affect, swallowing and speech disorders, and inability to initiate motion. Parkinson’s patients are notorious for falling during ‘freeze’ episodes because they cannot initiate movement to catch their balance. And they often fall hard because they cannot get their hands out to protect themselves (note Hillary’s head trauma episode).”

here are other possibilities, such as Progressive Supranuclear Palsey, which attacks people in Clinton’s age group and is similar to Parkinson’s. But she believes Clinton’s issues are neurological.

“What is absolutely clear to anyone willing to think is that Hillary’s health issue has been covered up and the American public has been lied to. But all the queen’s soldiers and all the queen’s men are failing to make it through the end game. Hillary now has handlers who help unfreeze her by running up on stage and reassuring her and touching her to get her mobile again.”

Hieb also cited noted Clinton is “being kept away from spontaneous crowds and questions which might trigger an event.”

“Why not come clean? Because people with Parkinson’s very frequently have dementia, cognitive deficits (reasoning problems), mood alterations and can have anger issues as well as the more obvious balance and motor problems. And when the ‘dementia’ label in any way attaches itself to Hillary, it is game over for her political future,” she said.

“I do not wish her ill, and I hope she will avail herself of the latest thinking in the subject of Parkinson’s and Parkinson-like disorders. If I were her, I’d go immediately to Florida for a visit with Dr. David Perlmutter, who for years has been really thinking outside the box with neurodegenerative diseases.”

WND has assembled the Big List of doctors who have raised questions about Clinton’s health, and two of them previously raised the issue of a possible diagnosis of Parkinson’s.

A board certified internist cited by Powerline blogger Scott Johnson suggests the pneumonia is a symptom of something much worse: a stroke or possibly Parkinson’s.

The physician wrote: “During my 19 years as a board certified internist I have taken care of many hundreds of patients with pneumonia. The story about Hillary Clinton being diagnosed with pneumonia raises a red flag as to the cause. It could simply have been a community acquired pneumonia, which means she contracted it as a healthy person living her usual life. This happens occasionally, even to healthy people. If this is the case the timing certainly is unfortunate for her given where we are in the election cycle though it doesn’t portend anything ominous.”

However, the internist noted there is another “more worrisome possibility.”

“I raise this second possibility because of Hillary’s history of neurological illnesses (blood clot in brain, concussion), hints raised on the Internet in Wikileaks documents and by others that she may have a neurological disease like Parkinson’s, and her by now well documented history of recurrent coughing fits. This second possibility is that she has an aspiration pneumonia.

“Aspiration pneumonia occurs when fluids and food particles that normally enter the esophagus instead enter the windpipe and lungs. It is commonly seen in neurological conditions like strokes and Parkinson’s disease or similar diseases where the nerves to the swallowing mechanism are not working properly. This is especially worrisome because it is likely to recur given the underlying, usually incurable disease process and because it can be a life-threatening event,” he said. “I consider aspiration pneumonia to be the more likely cause because it unifies all the pieces of disparate information that are available on Hillary’s medical condition. A diagnosis of aspiration pneumonia raises profoundly troubling implications for her possible election as president.”

Also, Dr. Ted Noel, at his blog VidZette, assembled a 16-minute video concluding the evidence suggests she has had Parkinson’s and has known about it for several years.

“Everything … fits the theory,” he said. “Video evidence is solid. [There’s] strong evidence of having advanced Parkinson’s disease.”

And that, he contended, makes her “medically unfit” for the Oval Office.

Clinton returned to the campaign trail on Thursday with a carefully scripted trip to North Carolina, even as polls showed Trump building a lead over her in battleground states.

The Democrat candidate’s plunge in support may partly be explained by the fact many people don’t believe her.

The Washington Times reported on Wednesday “half” of voters say Clinton “has given false information about her health.”

The report cited the Morning Consult poll, which found only 29 percent “said Mrs. Clinton has given accurate information about her personal health to the public.”

Former Secretary of State Colin Powell was told by a local political official, according to emails released this week, that Clinton was barely able to climb the steps to a podium to give a speech.

On Wednesday, when the Bardack letter was released, two physicians who comment on Fox News responded to questions on Sean Hannity’s show.

Dr. David Samadi noted that after last weekend’s collapse in New York, Clinton will need a medical team around her constantly.

“If it happens again, this would be a big problem for her,” he said.